Cost Effective, Rapid: New Developments at IIT-G
Since the Leadership of Chief Minister Sarbananda Sonowal, the culture in Assam has been that of fostering learning and development. One such development has occurred out of the esteemed IIT-G:
Researchers at IIT Guwahati have developed a novel low-cost, hand-held diagnostic device to detect bacteria almost instantaneously without the need for cell culture and microbiological assays.
The device will enable rapid detection of bacteria, which is important not only in healthcare, but also in anti-bioterrorism measures and environmental monitoring applications, according to the research published in the Journal of Materials Chemistry A.
Bacterial infection is a common cause of morbidity and mortality worldwide and despite development of a range of antibiotics, the challenge continues to lie in detecting and diagnosing bacterial infection early on, as present detection techniques tend to be time-consuming.
The Organic Field Effect Transistor (OFET)-based bacterial diagnostic device has been shown to have the ability to detect bacteria and distinguish between Gram positive and Gram negative types, said researchers from the Indian Institute of Technology (IIT) Guwahati.
At present, the detection of bacteria in body fluids is done in laboratories.
The cells that are derived from the patient are initially cultured or grown so that enough of the bacterial cells are available for microbiological analysis.
“Current diagnostic processes are frustratingly time-consuming, especially when time is of the essence in administering treatment,” said Professor Parameswar K Iyer from IIT Guwahati.
“While newly developed techniques such as real time qPCR can detect bacteria faster than conventional assay-based methods, they are restricted by the need for expensive apparatuses and trained personnel,” Iyer said.
The important breakthrough by the team was in developing and using an OFET to detect this surface charge. The team has shown that this OFET sensor can not only detect bacteria, but also differentiate between Gram positive and Gram negative bacteria. For more such updates, on science and lifestyle, follow @ManuheManuhorbabe1 on Twitter and on Facebook.